WORLD CLASS CARE
PTSD CARE helps change lives by connecting those in need with effective treatments performed by top rated physicians.
Nationwide Network – Most patients don’t need to travel a great distance to receive treatment
Excellent care – From physicians who are licensed, of course, but also fellowship trained and board-certified
Best of the best – We work with physicians who not only practice, but many also lecture, teach, and are involved in leading edge clinical research
Ketamine Infusion for Posttraumatic Stress Disorder (PTSD)
Ketamine infusion, unlike traditional treatment, can provide immediate temporary relief from some of the most serious symptoms associated with PTSD including anxiety, helplessness, and depression.
Treatments such as Valium or Xanax may decrease the anxiety, but also leave the patient feeling tired and lethargic.
SSRI antidepressants antidepressants may take weeks to work and have unwanted side effects.
- Talk therapy can be very helpful, but it takes time and doesn’t address the physical symptoms of PTSD.
- Ketamine is reported to provide immediate relief of symptoms in 70% of patients after only a single treatment.
What is Posttraumatic stress disorder (PTSD)?
PTSD is a condition that can occur when people have experienced or witnessed a traumatic event such as a natural disaster, serious accident, terrorist act, war/combat, rape, or violent personal assault.
Researchers know that tiny doses of ketamine can rapidly relieve depression symptoms when delivered via slow intravenous infusion. The first scholarly paper describing this discovery was published by Yale in 2000. Since then, dozens more studies have been conducted by Yale, the National Institutes of Health, the Veterans Administration, Harvard, Johns Hopkins, Mount Sinai Medical School, Oxford University, and more. Yale’s original findings have been reconfirmed many times.
“Recent data suggest that ketamine, given intravenously, might be the most important breakthrough in antidepressant treatment in decades.”
Director, National Institute of Mental Health
Many studies focused on the worst-of-the-worst cases; treatment-resistant patients who have suffered for years or decades. They have tried SSRIs, mood stabilizers, other medications, psychological counseling, as well as alternative treatments like acupuncture, with little to no benefit. Yet, an astonishing 70% of these extreme cases experience rapid relief from an IV infusion of ketamine.
Ketamine, like stellate ganglion block, can sound too good to be true for those who’ve suffered for years and given up hope of ever finding relief. However, the number of patients receiving IV infusions of ketamine, as well as the number of doctors offering this therapy, is growing rapidly and finally starting to reach the patients who need it most.
How does ketamine infusion help PTSD?
Ketamine is administered via slow infusion and unique conditions are created in the brain which trigger a delicate series of events. This cascade produces a protein that triggers rapid growth of neural connections by way of certain receptors and signaling pathways. Researchers suspect these growing neural connections, or “rewiring”, is part of the antidepressant effect. Depression is also highly correlated with chronic inflammation and ketamine is a powerful anti-inflammatory agent. It’s possible there are other factors that haven’t been identified yet.
How much does ketamine therapy cost?
- Unfortunately Ketamine Infusion is not covered by insurance when performed for the treatment of PTSD
- Insurance providers consider it an off-label use of the therapy
- UPDATE: Often covered by insurance in New York!
- Outside of New York, infusion ranges from $400 to $800 each
- To get the desired results many patients will require 4 to 6 infusions over a period of weeks, followed by maintenance infusions every 4 to 12 weeks
Stellate Ganglion Block
Single-blind studies show reductions in PTSD symptoms
“I had nightmares every night. I feel different now…like I’m back to normal”
“I’ve been feeling really good [since treatment]. I have more confidence and don’t have the negative thoughts. I’m calm.”
“I’m happy. I feel like a weight has been lifted”
Receive our FREE Patient Information Guide instantly!
Join Warriors & Survivors Enjoying Our Information
Consensus Guidelines on the Use of Intravenous Ketamine Infusions for Chronic Pain From the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists
Steven P. Cohen, MD,*† Anuj Bhatia, MBBS, MD,‡ Asokumar Buvanendran, MD,§ Eric S. Schwenk, MD,∥ Ajay D. Wasan, MD, MSc,** Robert W. Hurley, MD, PhD,†† Eugene R. Viscusi, MD,∥ Samer Narouze, MD, PhD,‡‡ Fred N. Davis, MD,§§∥∥ Elspeth C. Ritchie, MD, MPH,***††† Timothy R. Lubenow, MD,§ and William M. Hooten, MD‡‡‡
To visit this article Click Here
Berman RM, Cappiello A, Anand A, et al: Antidepressant effects of ketamine in depressed patients. Biological psychiatry 2000; 47:351-354
Aan Het Rot M, Zarate CA, Jr., Charney DS, et al: Ketamine for depression: where do we go from here? Biological psychiatry 2012; 72:537-547
Atigari OV,Healy D: Sustained antidepressant response to ketamine. BMJ case reports 2013; 2013:
Browne CA,Lucki I: Antidepressant effects of ketamine: mechanisms underlying fast acting novel antidepressants. Frontiers in pharmacology 2013; 4:161
Hasselmann HW: Ketamine as antidepressant? Current state and future perspectives. Current neuropharmacology 2014; 12:57-70
Ibrahim L, Diazgranados N, Franco-Chaves J, et al: Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2012; 37:1526-1533
Lara DR, Bisol LW,Munari LR: Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum 2013; 16:2111-2117
Murrough JW, Iosifescu DV, Chang LC, et al: Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. The American journal of psychiatry 2013; 170:1134-1142
Murrough JW, Perez AM, Pillemer S, et al: Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biological psychiatry 2013; 74:250-256
Niciu MJ, Luckenbaugh DA, Ionescu DF, et al: Subanesthetic dose ketamine does not induce an affective switch in three independent samples of treatment-resistant major depression. Biological psychiatry 2013; 74:e23-24
Okamoto N, Nakai T, Sakamoto K, et al: Rapid antidepressant effect of ketamine anesthesia during electroconvulsive therapy of treatment-resistant depression: comparing ketamine and propofol anesthesia. The journal of ECT 2010; 26:223-227
De Gioannis A,De Leo D: Oral ketamine augmentation for chronic suicidality in treatment-resistant depression. The Australian and New Zealand journal of psychiatry 2014;
Irwin SA,Iglewicz A: Oral ketamine for the rapid treatment of depression and anxiety in patients receiving hospice care. Journal of palliative medicine 2010; 13:903-908
Irwin SA, Iglewicz A, Nelesen RA, et al: Daily oral ketamine for the treatment of depression and anxiety in patients receiving hospice care: a 28-day open-label proof-of-concept trial. Journal of palliative medicine 2013; 16:958-965
McNulty JP, Hahn K: Compounded oral ketamine. International journal of pharmaceutical compounding 2012; 16:364-368
Paslakis G, Gilles M, Meyer-Lindenberg A, et al: Oral administration of the NMDA receptor antagonist S-ketamine as add-on therapy of depression: a case series. Pharmacopsychiatry 2010; 43:33-35 14
Bell RF, Dahl JB, Moore RA, et al: Peri-operative ketamine for acute post-operative pain: a quantitative and qualitative systematic review (Cochrane review). Acta anaesthesiologica Scandinavica 2005; 49:1405-1428
Bell RF, Dahl JB, Moore RA, et al: Perioperative ketamine for acute postoperative pain. The Cochrane database of systematic reviews 2006; CD004603
Bell RF, Eccleston C,Kalso E: Ketamine as adjuvant to opioids for cancer pain. A qualitative systematic review. Journal of pain and symptom management 2003; 26:867-875
Mathews TJ, Churchhouse AM, Housden T, et al: Does adding ketamine to morphine patient-controlled analgesia safely improve post-thoracotomy pain? Interactive cardiovascular and thoracic surgery 2012; 14:194-199
Mujic F, Von Heising M, Stewart RJ, et al: Mental capacity assessments among general hospital inpatients referred to a specialist liaison psychiatry service for older people. International psychogeriatrics / IPA 2009; 21:729-737
Kitamura T, Takahashi N: Ethical and conceptual aspects of capacity assessments in psychiatry. Current opinion in psychiatry 2007; 20:578-581